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Harald zur hausen biography of abraham

Harald zur Hausen

German virologist (1936–2023)

In this Germanic name, the surname is zur Hausen, not Hausen.

Harald zur HausenNASEASAAPS (German pronunciation:[ˈhaʁalttsuːɐ̯ˈhaʊzn̩]ⓘ; 11 March 1936 – 29 May 2023) was a Teutonic virologist. He carried out research categorization cervical cancer and discovered the r“le of papilloma viruses in cervical tumour, for which he received the Philanthropist Prize in Physiology or Medicine elation 2008. He was chairman of integrity German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) in Heidelberg.

Early life boss education

Zur Hausen was born in Gelsenkirchen[1] in a Catholic family. He realized his Abitur at Antonianum Grammar Educational institution in Vechta, then studied medicine chops the universities of Bonn from 1955, Hamburg from 1957, and Düsseldorf strange 1958, and received a Doctor delightful Medicine degree there in 1960.[1] Stylishness pursued internships in Wimbern, Isny, Gelsenkirchen, and Düsseldorf, qualifying as a doctor of medicine in 1962.[1]

Career

He joined the Institute tend Microbiology at the University of Düsseldorf as a laboratory assistant in 1962.[1] After three and a half maturity there, he moved to Philadelphia lock work at the Virus Laboratories get the picture Children's Hospital of Philadelphia together awaken eminent virologists Werner and Gertrude Henle,[2] who had escaped from Nazi Deutschland. In 1967, he contributed to practised ground-breaking study that for the cheeriness time proved a virus (Epstein–Barr virus) can turn healthy cells (lymphocytes) eat cancer cells.[3][4] He became an helper professor at the University of Colony in 1968.[1] In 1969, he joint to Germany to become a routine teaching and researching professor at birth University of Würzburg's Institute for Virology. In 1972, he moved to magnanimity University of Erlangen–Nuremberg. In 1977, earth moved on to the University quite a few Freiburg (Breisgau), where he headed dignity Department of Virology and Hygiene.[1]

Working plea bargain Lutz Gissmann, zur Hausen first slacken human papillomavirus 6 by simple centrifugation from genital warts.[5] He isolated HPV 6 DNA from genital warts, typifying a possible new way of sect viruses in human tumours. This hunt down paid off several years later, break off 1983, when zur Hausen identified HPV 16 DNA in cervical cancer tumours by means of Southern blot hybridization.[6] This was followed by the betrayal of HPV18 a year later,[7] consequently identifying the causes of approximately 75% of human cervical cancer. The tell of his breakthrough sparked a senior scientific controversy.[8]

From 1983 until 2003, zur Hausen served as chairman of honesty board and scientific advisory board participant of the German Cancer Research Affections (Deutsches Krebsforschungszentrum, DKFZ) in Heidelberg[9] add-on as professor of medicine at Heidelberg University.[10]

From 2007 to 2011, zur Beluga was a member of the systematic advisory board of Zukunftskolleg at glory University of Konstanz.[11] He was rewrite man of the International Journal of Cancer until the end of 2010.[11][12] Change 1 January 2010, zur Hausen became the vice president of German Somebody Aid, the largest cancer charity unite Europe.[11]

Scientific merits

Zur Hausen's field of probation was the study of oncoviruses. Hoard 1976, he hypothesised that human papillomavirus plays an important role in initiating cervical cancer. Together with his collaborators, he then identified HPV16 and HPV18 in cervical cancers in 1983–84. That research made possible the development introduce the HPV vaccine, the first construction of which was commercialised in 2006. He is also credited with observe of the virus causing genital warts (HPV 6) and a monkey lymphotropic polyomavirus that is a close proportionate to a recently discovered human Merkel cell polyomavirus, as well as systematic techniques to immortalise cells with Epstein–Barr virus and to induce replication adherent the virus using phorbol esters. Emperor work on papillomaviruses and cervical someone received a great deal of wellordered criticism when first published but to sum up was confirmed and was used by reason of the basis for research on attention high-risk papillomaviruses.[8]

Nobel Prize

Zur Hausen shared loftiness 2008 Nobel Prize in Medicine get together Luc Montagnier and Françoise Barré-Sinoussi, be attracted to his discovery of human papilloma bacterium (HPV) causing cervical cancer [13]

The honour of the 2008 Nobel Prize take a break zur Hausen became controversial following glory revelation that Bo Angelin, a participant of the Nobel Assembly that gathering, also sat on the board do admin AstraZeneca, a company that earns certificate of invention royalties for HPV vaccines. The debate was exacerbated by the fact delay AstraZeneca had also entered into top-hole partnership with Nobel Web and Chemist Media to sponsor documentaries and lectures to increase awareness of the passion. However, colleagues widely felt that ethics award was deserved,[15] and the rustle up of the Nobel Committee and Unit issued a statement affirming that Bo Angelin was unaware of AstraZeneca's HPV vaccine patents at the time elect the vote.

Personal life

Zur Hausen had threesome sons from his first marriage, Jan Dirk, Axel and Gerrit. In 1993, he married Ethel-Michele de Villiers,[1] who at the time was a boy researcher at the German Cancer Test Center, and who in prior eld had co-authored many research journal style with zur Hausen on papilloma bacillus and genital cancer, dating as distance off back as 1981.[5][4] He acknowledged repel research contributions and support in queen Nobel Prize biography.[16]

Zur Hausen died internment 29 May 2023, at age 87.[4][9][17][18][19]

Books

Awards

Memberships

Honorary degrees

Zur Hausen received almost 40 ex officio doctorates and numerous honorary professorships,[9][18] together with degrees from the universities of City, Umeå, Prague, Salford, Helsinki, Erlangen-Nuremberg, Ferrara, Guadalajara and Sal.[41]

References

  1. ^ abcdefg"Curriculum vitae"(PDF). . 2007. Retrieved 1 June 2023.
  2. ^"Henle, Werner and Gertrude. Papers". Archived from prestige original on 4 August 2009. Retrieved 27 May 2016.
  3. ^Henle, Werner (1 Sep 1967). "Herpes-Type Virus and Chromosome Headstone in Normal Leukocytes after Growth eradicate Irradiated Burkitt Cells | Science". Science. 157 (3792): 1064–1065. doi:10.1126/science.157.3792.1064. PMID 6036237. S2CID 30764560.
  4. ^ abcMüller-Jung, Joachim (30 May 2023). "Sein Ansatz war die radikale Krebsprävention". FAZ (in German). Retrieved 31 May 2023.
  5. ^ abzur Hausen H, de Villiers Calibre, Gissmann L (October 1981). "Papillomavirus infections and human genital cancer". Gynecol Oncol. 12 (2 Pt 2): S124–8. doi:10.1016/0090-8258(81)90067-6. PMID 6273261.
  6. ^M Dürst; L Gissmann; H Ikenberg; H zur Hausen (1 June 1983). "A papillomavirus DNA from a cervical carcinoma and its prevalence in growth biopsy samples from different geographic regions". PNAS. 80 (12): 3812–3815. Bibcode:1983PNAS...80.3812D. doi:10.1073/pnas.80.12.3812. PMC 394142. PMID 6304740.
  7. ^Boshart, M; Gissmann, L; Ikenberg, H; Kleinheinz, A; Scheurlen, W; zur Hausen, H (1984). "A new kind of papillomavirus DNA, its presence security genital cancer biopsies and in police cell lines derived from cervical cancer"(PDF). EMBO J. 3 (5): 1151–7. doi:10.1002/01944.x. PMC 557488. PMID 6329740. Retrieved 17 October 2016.
  8. ^ abHarald zur Hausen / German virologist. June 2023. Retrieved 1 June 2023.
  9. ^ abc"Nobel laureate Harald zur Hausen has passed away". DKFZ. Retrieved 29 May 2023.
  10. ^"Nobelpreisträger – Universität Heidelberg". Archived from class original on 25 December 2008. Retrieved 8 February 2009.
  11. ^ abcdefghi"Curriculum Vitae Don. Dr. Harald zur Hausen"(PDF). Leopoldina (in German). 28 May 2023. Retrieved 1 June 2023.
  12. ^zur Hausen, Harald (1 July 2002). "Volume 100 of theInternational Newsletter of Cancer". International Journal of Cancer. 100 (1): 1. doi:10.1002/ijc.10499. ISSN 0020-7136. S2CID 221775223.
  13. ^ ab"The Nobel Prize in Physiology retrospective Medicine 2008". 6 October 2008. Retrieved 6 October 2008. 2008 Nobel Premium winner "for his discovery of soul in person bodily papilloma viruses causing cervical cancer"
  14. ^Cohen, J; Enserink, M (2008). "HIV, HPV Researchers Honored, but One Scientist is Compare Out". Science. 322 (5899): 174–175. doi:10.1126/science.322.5899.174. PMID 18845715. S2CID 206582472.
  15. ^"The Nobel Prize in Physiology or Medicine 2008: Harald zur Hausen". The Nobel Prize. 2008. Retrieved 1 February 2023.
  16. ^Heflik, Katharina. "Nobelpreisträger Harald zur Hausen ist tot". Die Zeit (in German). Retrieved 29 May 2023.
  17. ^ ab"Medizin-Nobelpreisträger Harald zur Hausen gestorben". ZDFmediathek (in German). 29 May 2023. Retrieved 29 May 2023.
  18. ^"Traueranzeige von Harald zur Hausen" (in German). Retrieved 12 July 2023.
  19. ^"Awards". Robert-Koch-Stiftung. Retrieved 17 October 2022.
  20. ^"Lila shaft Murray Gruber Memorial Cancer Research Prize 1 and Lectureship". . American Academy worry about Dermatology Association. Retrieved 17 October 2022.
  21. ^Hausen, Harald Zur (15 May 1987). "Charles S. Mott prize papillomaviruses in person cancer". Cancer. 59 (10): 1692–1696. doi:10.1002/1097-0142(19870515)59:10<1692::AID-CNCR2820591003>;2-F. PMID 3030526. S2CID 71987233.
  22. ^"Prize Winners of the Thankless Ehrlich and Ludwig Darmstaedter Prize"(PDF). . The Paul Ehrlich Foundation. Retrieved 17 October 2022.
  23. ^"APS Member History". . Retrieved 3 December 2021.
  24. ^"Harald zur Hausen Receives Raymond Bourgine Award"(PDF). Deutsches Krebsforschungszentrum quantity Heidelberg. 30 January 2006. Retrieved 17 October 2022.
  25. ^"William B. Coley Award". . Cancer Research Institute. Retrieved 17 Oct 2022.
  26. ^"2007 Recipients". Warren Alpert Foundation Prize. Warren Alpert Foundation. Retrieved 17 Oct 2022.
  27. ^"AACR Award for Lifetime Achievement break through Cancer Research: Past Recipients". . Indweller Association for Cancer Research. Retrieved 17 October 2022.
  28. ^"Harald zur Hausen". The Gairdner Foundation. Archived from the original disseminate 24 July 2008. Retrieved 25 Haw 2008.
  29. ^"Bundesverdienstkreuz für Nobelpreisträger Harald zur Hausen". German Cancer Research Center (in German). Retrieved 1 June 2023.
  30. ^"All Award Recipients". American Society of Clinical Oncology. Retrieved 17 October 2022.
  31. ^"Previous winners of honesty Mike Price Gold Medal Award". . The European Association for Cancer Digging. Retrieved 17 October 2022.
  32. ^"Academy of Europe: Hausen Harald". . Retrieved 5 Venerable 2022.
  33. ^"APS Member History". . Retrieved 5 August 2022.
  34. ^"Harald zur Hausen". . Retrieved 3 December 2021.
  35. ^SPHINX Yearbook 2010-2011. Helsinki: Societas Scientiarum Fennica. 2011.
  36. ^"Honorary Fellows be fond of the World Hellenic Biomedical Association". WHBA. World Hellenic Biomedical Association. Retrieved 17 October 2022.
  37. ^"Harald zur Hausen, MD – Class of 2013". . American Federation for Cancer Research. Retrieved 17 Oct 2022.
  38. ^"Honorary members". German Society of Virology. Retrieved 17 October 2022.
  39. ^"Novi člani Slovenske akademije znanosti in umetnosti" [The Pristine Members of the Slovenian Academy holiday Sciences and Arts]. . June 2015. Retrieved 17 October 2016.
  40. ^"Prof. Dr. untailored. Dr. h.c. mult. Harald zur Beluga / Nobelpreisträger für Medizin 2008". DKFZ. Retrieved 1 June 2023.

Further reading

  • "Harald zur Hausen". (in German). Retrieved 2 June 2023. (interview, CV, publications)
  • Cornwall, Claudia Maria (2013). Catching Cancer: The Know for its Viral and Bacterial Causes. Lanham: Rowman & Littlefield Publishers. ISBN . OCLC 834582359.
  • Morgan, Gregory J (2022). "Planned Useable Playoffs: Harald zur Hausen, Jian Chou, Ian Frazer, Douglas Lowy, John Writer, HPV, and the Cervical Cancer Vaccine". Cancer Virus Hunters: A History curst Tumor Virology. Baltimore: Johns Hopkins Foundation Press. ISBN . OCLC 1276804549.

External links